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Babies who die from Sudden Infant Death Syndrome (SIDS), also known as cot death or crib death make low amount of message-carrying brain chemical serotonin needed to regulate sleep, breathing, heart rate, US researchers said.
The tissue came from the medulla, a region at the base of the brain that regulates basic functions such as body temperature, breathing, blood pressure and heart rate. Dr. Hannah Kinney of Harvard Medical School and Children's Hospital Boston and colleagues found that serotonin levels were 26 percent lower in tissue from babies who died of SIDS than those who died from other causes, and they also found low levels of the enzyme tryptophan hydroxylase, which is needed to make serotonin.
"We have known for many years that placing infants to sleep on their backs is the single most effective way to reduce the risk of SIDS," says Dr. Alan Guttmacher, director of the National Institute of Child Health and Human Development, which funded the study. That's why, US researchers hope the study will lead to a test that measures a baby's serotonin levels, making it possible to identify children at highest risk for SIDS. Thus, to avoid the high risk of SIDS, parents and caregivers should put infants on their backs to sleep, avoid keeping rooms too warm and keep loose blankets and pillows away from infants.
The tissue came from the medulla, a region at the base of the brain that regulates basic functions such as body temperature, breathing, blood pressure and heart rate. Dr. Hannah Kinney of Harvard Medical School and Children's Hospital Boston and colleagues found that serotonin levels were 26 percent lower in tissue from babies who died of SIDS than those who died from other causes, and they also found low levels of the enzyme tryptophan hydroxylase, which is needed to make serotonin.
"We have known for many years that placing infants to sleep on their backs is the single most effective way to reduce the risk of SIDS," says Dr. Alan Guttmacher, director of the National Institute of Child Health and Human Development, which funded the study. That's why, US researchers hope the study will lead to a test that measures a baby's serotonin levels, making it possible to identify children at highest risk for SIDS. Thus, to avoid the high risk of SIDS, parents and caregivers should put infants on their backs to sleep, avoid keeping rooms too warm and keep loose blankets and pillows away from infants.
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